Article

Single cell gene expression profiling of nasal ciliated cells reveals distinctive biological processes related to epigenetic mechanisms in patients with severe COVID-19

2021-12-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> To explore the molecular processes associated with cellular regulatory programs in patients with COVID-19, including gene activation or repression mediated by epigenetic mechanisms. We hypothesized that a comprehensive gene expression profiling of nasopharyngeal epithelial cells might expand understanding of the pathogenic mechanisms of severe COVID-19. <h4>Methods</h4> We used...

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Literature Corpus work: 1e348fe6-2af7-5f51-be50-c8d7421446a7
DOI: 10.1101/2021.12.08.21267478

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