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Transcriptomics unravels molecular changes associated with cilia and COVID-19 in chronic rhinosinusitis with nasal polyps

21 Apr 2023

Abstract excerpt

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common upper respiratory tract complication where the pathogenesis is largely unknown. Herein, we investigated the transcriptome profile in nasal mucosa biopsies of CRSwNP patients and healthy individuals. We further integrated the transcriptomics data with genes located in chromosomal regions containing genome-wide significant gene variants for COVID-19....

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Cystic Fibrosis Research Advances
IgG4-Related and Inflammatory Diseases
Sinusitis and nasal conditions

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37085563
DOI: 10.1038/s41598-023-32944-3

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