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Mitochondrial fission, integrity and completion of mitophagy require separable functions of Vps13D in <i>Drosophila</i> neurons

2020-01-22

Abstract excerpt

A healthy population of mitochondria, maintained by proper fission, fusion, and degradation, is critical for the long-term survival and function of neurons. Here, our discovery of mitophagy intermediates in fission-impaired Drosophila neurons brings new perspective into the relationship between mitochondrial fission and mitophagy. Neurons lacking either the ataxia disease gene Vps13D or the dynamin related protei...

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Identifiers and source

Literature Corpus work
1e11f74a-bcb7-5f2f-b12e-bcb5d6ad43a7
DOI
10.1101/2020.01.21.914523
Open publication

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Mitochondrial fission, integrity and completion of mitophagy require separable functions of Vps13D in <i>Drosophila</i> neuronsDOI 10.1101/2020.01.21.914523
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