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Article

Understanding oocyte ageing: can we influence the process as clinicians?

22 Mar 2021

Abstract excerpt

PURPOSE OF REVIEW: Oocyte quality is rate-limiting for pregnancy success and declines with age. Here, I review animal-study evidence showing dramatic reversal of oocyte ageing with mitochondrial nutrients and explore clinical evidence related to their usage. RECENT FINDINGS: Oocyte ageing is strongly tied to mitochondrial dysfunction and oxidative stress. Quality-defining events occur over a protracted period...

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Identifiers

PMID: 33769423
DOI: 10.1097/gco.0000000000000708

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