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The impact of telomere shortening on human hippocampal neurogenesis: Implications for cognitive function and psychiatric disorder risk

2020-04-20

Abstract excerpt

Telomere shortening is one hallmark of cell ageing that can limit the proliferative capacity of cell populations and increase risk for age-related disease. It has been hypothesized that short telomeres, and subsequently a limited proliferative capacity of hippocampal progenitor cells, could contribute to smaller hippocampal volumes and impaired cognition, amongst psychiatric disorder patients. The current study em...

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Literature Corpus work
1de1ef5f-7cc4-51b3-9f86-f7a39f2fd6cd
DOI
10.1101/2020.04.19.049411
Open publication

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The impact of telomere shortening on human hippocampal neurogenesis: Implications for cognitive function and psychiatric disorder riskDOI 10.1101/2020.04.19.049411
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