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Reduced Telomere Length in Neurodegenerative Disorders May Suggest Shared Biology

26 Dec 2014

Abstract excerpt

Early cell death is a feature of neurodegenerative disorders. Telomere shortening is related to premature cellular senescence and could be a marker for cellular pathology in neurological diseases. Relative telomere length in dementia (N=70), Huntington's disease (N=35), ataxia telangiectasia (N=9), and age-group matched control samples (N=105) was measured as relative telomere copy/single copy gene ratios....

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Share to Genetics, Aging, and Longevity in Model Organisms
Share to Mitochondrial Function and Pathology
Share to Telomeres, Telomerase, and Senescence

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PMID: 25541866
DOI: 10.1176/appi.neuropsych.13100240

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