Article

Conceptual Model of Stage-Dependent Transition in Rheumatoid Arthritis: A Threshold Framework for Ultra-Early Intervention

2026-03-11

Abstract excerpt

Rheumatoid arthritis (RA) is traditionally diagnosed once clinical joint swelling becomes apparent. However, many patients report non-localized stiffness in very early stage then preceding overt synovitis. The transitional processes linking systemic autoimmunity to localized joint inflammation remain incompletely conceptualized. This study proposed a conceptual stage-dependent transition model distinguishing a rev...

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Literature Corpus work: 1de131d7-8a4a-5d03-bd51-b3c50a13d062
DOI: 10.20944/preprints202603.0783.v1

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