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Article

Neither ultrasound synovitis nor clinical-ultrasound phenotypes of established rheumatoid arthritis predict response to targeted therapy.

Rheumatology (Oxford, England) - 1 Dec 2025

Fitton John, Melville Andrew, Di Matteo Andrea, Nam Jackie, Dass Shouvik, Saleem Benazir, Shukla Rudresh, Emery Paul, Wakefield Richard J, Hensor Elizabeth M A, Buch Maya H

Abstract excerpt

OBJECTIVES: To identify patient sub-phenotypes using clinical and imaging measures in established rheumatoid arthritis (RA) and to establish if baseline ultrasound synovitis and/or baseline patient sub-phenotypes predicts response to targeted therapy (TT). METHODS: This was an observational cohort study of consecutively recruited patients with established RA starting TT. Participants received clinical assessment,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40568845
DOI: 10.1093/rheumatology/keaf315
PMCID: PMC12671869

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