Back to search

Article

Development and Validation of LAMP Primer Sets for Rapid and Correct Identification of <i>Aspergillus fumigatus</i> Carrying the <i>cyp51A</i> TR <sub>46</sub> Azole Resistance Gene

2021-03-03

Abstract excerpt

<h4>ABSTRACT</h4> Infections due to triazole resistant Aspergillus fumigatus are increasingly reported worldwide and are associated with treatment failure and mortality. The principal class of azole resistant isolates is characterized by the presence of tandem repeats of 34 bp or 46 bp (TR 34 or TR 46 ) within the promoter region of the cyp51A gene. Loop-mediated isothermal amplification (LAMP) is a widely us...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1d8b204e-eaa9-5927-93be-e6cd9567c98c
DOI
10.1101/2021.03.02.433685
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Development and Validation of LAMP Primer Sets for Rapid and Correct Identification of <i>Aspergillus fumigatus</i> Carrying the <i>cyp51A</i> TR <sub>46</sub> Azole Resistance GeneDOI 10.1101/2021.03.02.433685
Incidence of Cyp51 A key mutations in Aspergillus fumigatus-a study on primary clinical samples of immunocompromised patients in the period of 1995-2013.Semantic proximity
Detection of Substitutions at 98th, 121st, and 289th Amino Acid Residues in Cyp51A using Cycling Probes.Semantic proximity
First clinical isolation report of azole-resistant Aspergillus fumigatus with TR34/L98H-type mutation in Japan.Semantic proximity
Molecular Diagnosis of Invasive Aspergillosis and Detection of Azole Resistance by a Newly Commercialized PCR KitSemantic proximity
Phenotypic and Molecular Characterization of Three Clinical Voriconazole- Resistant Aspergillus fumigatus Isolates Harboring TR46/M143L Mutations in cyp51ASemantic proximity
Examination of cyp51A and cyp51B expression level of the first Polish azole resistant clinical Aspergillus fumigatus isolateSemantic proximity
Azole-resistant Aspergillus fumigatus Containing a 34-bp Tandem Repeat in cyp51A Promoter is Isolated from the Environment in JapanSemantic proximity
First description of azole-resistant Aspergillus fumigatus due to TR46/Y121F/T289A mutation in France.Semantic proximity
Development of multiplex real-time PCR for rapid identification and quantitative analysis of Aspergillus speciesSemantic proximity
Development of novel PCR assays to detect azole resistance-mediating mutations of the Aspergillus fumigatus cyp51A gene in primary clinical samples from neutropenic patients.Semantic proximity
Molecular Detection of Azole-Resistant Aspergillus fumigatus in Clinical SamplesSemantic proximity
Antifungal Susceptibility and <em>cyp51A</em> Gene Variation Analysis of <em>Aspergillus fumigatus</em> Isolated from Soils in Tea-Growing Areas of Guizhou, ChinaSemantic proximity
Select a neighboring publication to make it the new centre.