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Article

First clinical isolation report of azole-resistant Aspergillus fumigatus with TR34/L98H-type mutation in Japan.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Aug 2017

Toyotome Takahito, Hagiwara Daisuke, Kida Hideyuki, Ogi Takahiro, Watanabe Akira, Wada Terumi, Komatsu Ryoichi, Kamei Katsuhiko

Abstract excerpt

Recently, azole-resistant Aspergillus fumigatus containing a 34-bp or 46-bp tandem repeat in the promoter region of cyp51A combined with amino acid substitution(s) has appeared in the environment worldwide, including several Asian countries. In this study, we isolated the 34-bp tandem repeat-containing azole-resistant A. fumigatus strain OKH50 from a patient in Japan in May 2016. The patient had not been treated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28109740
DOI: 10.1016/j.jiac.2016.12.004

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