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Activation of Microbiota Sensor- Free Fatty Acid Receptor 2 Signaling Ameliorates Amyloid-Β Induced Neurotoxicity by Modulating Proteolysis/Senescence Axis

2020-12-24

Abstract excerpt

Gut microbiota and its metabolites like short chain fatty acids (SCFAs) are linked with pathology of Alzheimer’s disease (AD)- a debilitating public health problem in older adults. However, strategies to beneficially modulate gut microbiota and its sensing signaling pathways remain largely unknown. Here, we screened, validated and established the agonists of free fatty acid receptor 2 (FFAR2) signaling, whic...

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Literature Corpus work
1d8ae0d3-3084-58e3-96dc-edff3dc4098b
DOI
10.20944/preprints202012.0635.v1
Open publication

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Activation of Microbiota Sensor- Free Fatty Acid Receptor 2 Signaling Ameliorates Amyloid-Β Induced Neurotoxicity by Modulating Proteolysis/Senescence AxisDOI 10.20944/preprints202012.0635.v1
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