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Regulation of prostaglandin receptor expression in human monocytic cells following inflammatory activation

2015-01-01

Abstract excerpt

Inflammatory cells such as monocytes can be activated by bacteria leading to the release of pro-inflammatory cytokines, particularly tumour necrosis factor-α (TNF-α) and interleukin-1 (IL-1β) which sequentially induce prostaglandin (PG) production. It has been shown that PGs, especially PGE2 and PGD2, can potently suppress the production of cytokines when added exogenously or produced endogenously by negative-feed...

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Literature Corpus work
1d651317-ba2d-5053-89c5-b2fa3ba7e8be
DOI
10.48730/6vm6-y853
Open publication

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