Article

Functional variants in hematopoietic transcription factor footprints and their roles in the risk of immune system diseases

2021-03-22

Abstract excerpt

Genome-wide association studies (GWAS) have been performed to identify thousands of variants in the human genome as disease risk markers, but functional variants that actually affect gene regulation and their genomic features remain largely unknown. Here we performed a comprehensive survey of functional variants in the regulatory elements of the human genome. We integrated hematopoietic transcription factor (TF) f...

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Literature Corpus work: 1d0f2497-45d2-5d96-a38e-8afae11eb3e6
DOI: 10.1101/2021.03.22.436360

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