Article

Oral Baricitinib in the Treatment of Cutaneous Lichen Planus

2024-01-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Cutaneous lichen planus (LP) is a recalcitrant, difficult-to-treat, inflammatory skin disease characterized by pruritic, flat-topped, violaceous papules on the skin. Baricitinib is an oral Janus kinase (JAK) 1/2 inhibitor that interrupts the signaling pathway of interferon (IFN)-γ, a cytokine implicated in the pathogenesis of LP. <h4>Methods</h4> In this phase II trial, twe...

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Literature Corpus work: 1cc7bf06-74ab-546c-87c7-7471e716a8bd
DOI: 10.1101/2024.01.09.24300946

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