Article

MiR-505-3p is a Repressor of the Puberty Onset in Female Mice miR-505-3p and the puberty onset

2018-08-28

Abstract excerpt

Puberty onset is a complex trait regulated by multiple genetic and environmental factors. In this study, we narrowed a puberty related QTL down to a 1.7 Mb region on chromosome X in female mice and inferred miR-505-3p as the functional gene. We conducted ectopic expression of miR-505-3p in the hypothalamus of prepubertal female mice through lentivirus-mediated orthotopic injection. The impact of miR-505-3p on fema...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1cbde6bb-c479-5915-b6da-7cadacc6f1d3
DOI: 10.1101/402784

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MiR-505-3p is a Repressor of the Puberty Onset in Female Mice miR-505-3p and the puberty onsetDOI 10.1101/402784Read

miR-505-3p is a repressor of puberty onset in female miceSemantic proximity Read

Emerging Genetic and Epigenetic Mechanisms Underlying Pubertal Maturation in AdolescenceSemantic proximity Read

Genetic and Epigenetic Control of PubertySemantic proximity Read

A novel model of central precocious puberty disease: Paternal MKRN3 gene-modified rabbit.Semantic proximity Read

The Key Roles of Makorin RING Finger Protein 3 (MKRN3) During the Development of Pubertal Initiation and Central Precocious Puberty (CPP).Semantic proximity Read

Epigenetics: A New Player in the Regulation of Mammalian PubertySemantic proximity Read

Variation in the Timing of Puberty: Clinical Spectrum and Genetic InvestigationSemantic proximity Read

A new pathway in the control of the initiation of puberty: the MKRN3 gene.Semantic proximity Read

Gene expression profiling of puberty-associated genes reveals abundant tissue and sex-specific changes across postnatal developmentSemantic proximity Read

Control of puberty: genetics, endocrinology, and environment.Semantic proximity Read

Variation in the timing of puberty: clinical spectrum and genetic investigation.Semantic proximity Read

Disentangling puberty: novel neuroendocrine pathways and mechanisms for the control of mammalian pubertySemantic proximity Read