Article
A new pathway in the control of the initiation of puberty: the MKRN3 gene.
Journal of molecular endocrinology - 1 Jun 2015
Abreu Ana Paula, Macedo Delanie B, Brito Vinicius N, Kaiser Ursula B, Latronico Ana Claudia
Abstract excerpt
Pubertal timing is influenced by complex interactions among genetic, nutritional, environmental, and socioeconomic factors. The role of MKRN3, an imprinted gene located in the Prader-Willi syndrome critical region (chromosome 15q11-13), in pubertal initiation was first described in 2013 after the...
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