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Article

Emerging Genetic and Epigenetic Mechanisms Underlying Pubertal Maturation in Adolescence

1 Mar 2019

Abstract excerpt

The adolescent transition begins with the onset of puberty which, upstream in the brain, is initiated by the gonadotropin-releasing hormone (GnRH) pulse generator that activates the release of peripheral sex hormones. Substantial research in human and animal models has revealed a myriad of cellular networks and heritable genes that control the GnRH pulse generator allowing the individual to begin the process of...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 30869843
DOI: 10.1111/jora.12385

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