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Article

Hereditary spastic paraplegia type 11: Clinicogenetic lessons from 339 patients.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Mar 2021

Du Juan

Abstract excerpt

Hereditary spastic paraplegia type 11 (SPG11) is the most common subtype of autosomal recessive hereditary spastic paraplegia (HSP), to date, there are more than 181 different KIAA1840 gene mutations detected, and yet the genetic landscape of SPG11 is far from complete. To find the clinical and genetic characteristics of SPG11, we performed a reanalysis of the clinical features and genotype-phenotype correlations...

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Identifiers

PMID: 33581793
DOI: 10.1016/j.jocn.2020.11.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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