Back to search

Article

Multiplatform Computational Analysis of Mast Cells in Adrenocortical Carcinoma Tumor Microenvironment

2021-02-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Immunotherapeutic response failure of adrenocortical carcinomas (ACC) highlights a need for novel strategies targeting immune cell populations in the tumor microenvironment (TME) to overcome tumor resistance and enhance therapeutic response. A recent study explored a new link between tumor mast cell (MC) infiltration and improved outcomes in patients with ACC. We further d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1c77e6cb-6feb-51a8-b3ee-27253a543ead
DOI
10.1101/2021.02.09.430462
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Multiplatform Computational Analysis of Mast Cells in Adrenocortical Carcinoma Tumor MicroenvironmentDOI 10.1101/2021.02.09.430462
Multiplatform Integrative Analyses of Immunosuppressive Signatures in Cortisol-secreting Adrenocortical CarcinomaSemantic proximity
The Characteristics of Tumor Microenvironment Predict Survival and Response to Immunotherapy in Adrenocortical CarcinomasSemantic proximity
Adrenocortical Carcinoma Steroid Profiles: In Silico Pan-Cancer Analysis of TCGA Data Uncovers Immunotherapy Targets for Potential Improved OutcomesSemantic proximity
Elucidating the role of tumor-associated ALOX5+ mast cells with transformative function in cervical cancer progression via single-cell RNA sequencingSemantic proximity
Large-scale bulk RNA-seq analysis defines immune evasion mechanism related to mast cell in gliomasSemantic proximity
Identification of prognostic genes in adrenocortical carcinoma microenvironment based on bioinformatic methodsSemantic proximity
Ferroptosis Regulators and Tumor Microenvironment Immune Cell Infiltration Characterization in Adrenocortical CarcinomaSemantic proximity
Verification of Genetic Differences and Immune Cell Infiltration Subtypes in Neuroblastoma Tumor Microenvironment for ImmunotherapySemantic proximity
Analysis of m6A-Related Signatures in the Tumor Immune Microenvironment and Identification of Clinical Prognostic Regulators in Adrenocortical Carcinoma.Semantic proximity
Molecular Profiling and the Impact of Treatment on Outcomes in Adenoid Cystic Carcinoma Type I and II.Semantic proximity
Single-cell profiling reveals the sustained immune infiltration, surveillance, and tumor heterogeneity of infiltrative BCCSemantic proximity
Comprehensive analysis of an ATF/CREB family-based signature with regard to prognosis and immune feature in adrenocortical carcinomaSemantic proximity
Select a neighboring publication to make it the new centre.