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Large-scale bulk RNA-seq analysis defines immune evasion mechanism related to mast cell in gliomas

8 Sept 2022

Abstract excerpt

Accumulating evidence has demonstrated that the immune cells have an emerging role in controlling anti-tumor immune responses and tumor progression. The comprehensive role of mast cell in glioma has not been illustrated yet. In this study, 1,991 diffuse glioma samples were collected from The Cancer Genome Atlas (TCGA) and the Chinese Glioma Genome Atlas (CGGA). xCell algorithm was employed to define the mast...

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PMID: 36159780
DOI: 10.3389/fimmu.2022.914001

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