Article

Mechanisms of <i>Igf2</i> inhibition in thymic epithelial cells infected by coxsackievirus CV-B4

2020-01-12

Abstract excerpt

<h4>ABSTRACT</h4> Epidemiological studies have evidenced a link between type 1 diabetes (T1D) and infections by enteroviruses, especially with coxsackievirus B4 (CV-B4). CV-B4 is able to infect human and murine thymic epithelial cells (TECs) and, in a murine TEC line, we have shown that the diabetogenic strain CV-B4 E2 decreases transcription of insulin-like growth factor 2 gene ( Igf2 ), coding for the self-pep...

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Literature Corpus work: 1c5a83ac-0387-5922-ae97-8a94bf04e7b3
DOI: 10.1101/2020.01.10.902684

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