Article
Heterocomplexes between the Atypical Chemokine MIF and the CXC-Motif Chemokine CXCL4L1 Regulate Inflammation and Thrombus Formation
2022-02-07
Abstract excerpt
<title>Abstract</title> <p>To fulfil its orchestrating function in immune cell trafficking, a network of chemokines and receptors capitalizes on specificity, redundancy, and functional selectivity. The discovery of heteromeric interactions in the chemokine interactome has expanded the complexity within the network. Moreover, some inflammatory mediators, not structurally linked to classical chemokines, bind to che...
Topics
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- Atherosclerosis and Cardiovascular Diseases
- Cell Adhesion Molecules Research
- Chemokine receptors and signaling
- Cytokine Signaling Pathways and Interactions
- Glycosylation and Glycoproteins Research
- Macrophage Migration Inhibitory Factor
- Monoclonal and Polyclonal Antibodies Research
- T-cell and B-cell Immunology
Identifiers and source
- Literature Corpus work
- 1bfed070-3c99-5a5c-83b1-5fae9f35e940
- DOI
- 10.21203/rs.3.rs-1300172/v1
