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Article

Role and implications of the CXCL12/CXCR4/CXCR7 axis in atherosclerosis: still a debate

1 Jan 2021

Abstract excerpt

Atherosclerosis is one of the leading causes of mortality and morbidity worldwide. Chemokines and their receptors are implicated in the pathogenesis of atherosclerosis. CXCL12 is a member of the chemokine family exerting a myriad role in atherosclerosis through its classical CXCR4 and atypical ACKR3 (CXCR7) receptors. The modulatory and regulatory functional spectrum of CXCL12/CXCR4/ACKR3 axis in atherosclerosis...

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PMID: 34494495
DOI: 10.1080/07853890.2021.1974084

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