Article

Multiplex Assessment of Protein Variant Abundance by Massively Parallel Sequencing

2018-01-16

Abstract excerpt

<h4>ABSTRACT</h4> Determining the pathogenicity of human genetic variants is a critical challenge, and functional assessment is often the only option. Experimentally characterizing millions of possible missense variants in thousands of clinically important genes will likely require generalizable, scalable assays. Here we describe Variant Abundance by Massively Parallel Sequencing (VAMP-seq), which measures the ef...

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Literature Corpus work: 1bf693fb-1265-5499-a7a7-dbc108949fe8
DOI: 10.1101/211011

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