Article

Homozygous SPAG6 Variants Can Induce Nonsyndromic Asthenoteratozoospermia With Severe MMAF

2021-10-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Multiple morphological abnormalities of the sperm flagella (MMAF) is a subtype of severe asthenoteratozoospermia with poorly understood genetic etiology. SPAG6 is a core axonemal component that plays a critical role in the formation of cilia and sperm flagella. Previous studies have reported that mutations in <italic>SPAG6</italic> cause primary ciliary dyskines...

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Literature Corpus work: 1beee86f-9106-51c0-b250-0323ba15e9f8
DOI: 10.21203/rs.3.rs-991517/v1

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