Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Proteomics and Bioinformatics Identify Drug-Resistant-Related Genes with Prognostic Potential in Cholangiocarcinoma

8 Aug 2024

Abstract excerpt

Drug resistance is a major challenge in the treatment of advanced cholangiocarcinoma (CCA). Understanding the mechanisms of drug resistance can aid in identifying novel prognostic biomarkers and therapeutic targets to improve treatment efficacy. This study established 5-fluorouracil- (5-FU) and gemcitabine-resistant CCA cell lines, KKU-213FR and KKU-213GR, and utilized comparative proteomics to identify...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Mechanisms of cancer metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39199357
DOI: 10.3390/biom14080969

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proteomics and Bioinformatics Identify Drug-Resistant-Related Genes with Prognostic Potential in CholangiocarcinomaPMID 39199357Read ↗

Transcriptomic analysis and identification of prognostic biomarkers in cholangiocarcinomaSemantic proximity Read ↗

Molecular mechanisms and genetic features of cholangiocarcinoma: implications for targeted therapeutic strategiesSemantic proximity Read ↗

Signalling networks in cholangiocarcinoma: Molecular pathogenesis, targeted therapies and drug resistanceSemantic proximity Read ↗

Precision Medicine in Cholangiocarcinoma: Past, Present, and FutureSemantic proximity Read ↗

Biological and genetic characterization of a newly established human primary multidrug-resistant distal cholangiocarcinoma cell line, CBC3T-6.Semantic proximity Read ↗

Biliary cancer: gateway to comprehensive molecular profiling.Semantic proximity Read ↗

Molecular biology of cholangiocarcinoma and its implications for targeted therapy in patient management.Semantic proximity Read ↗

Bioinformatics Combined with Quantitative Proteomics Analyses and Identification of Potential Biomarkers in CholangiocarcinomaSemantic proximity Read ↗

Developments in FGFR and IDH inhibitors for cholangiocarcinoma therapy.Semantic proximity Read ↗

Evolution of Treatment in Advanced Cholangiocarcinoma: Old and New towards Precision Oncology.Semantic proximity Read ↗

Establishment and Characterization of a New Intrahepatic Cholangiocarcinoma Cell Line Resistant to GemcitabineSemantic proximity Read ↗

Knockdown of cullin 3 inhibits progressive phenotypes and increases chemosensitivity in cholangiocarcinoma cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.