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Article

Molecularly Guided Drug Repurposing for Cholangiocarcinoma: An Integrative Bioinformatic Approach

29 Jan 2022

Abstract excerpt

BACKGROUND: Cholangiocarcinoma (CCA) has a complex immune microenvironment architecture, thus possessing challenges in its characterization and treatment. This study aimed to repurpose FDA-approved drugs for cholangiocarcinoma by transcriptomic-driven bioinformatic approach. METHODS: Cox-proportional univariate regression was applied to 3017 immune-related genes known a priori to identify a list of...

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PMID: 35205315
DOI: 10.3390/genes13020271

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