Article

Maximum Likelihood Estimation of Biological Relatedness from Low Coverage Sequencing Data

2015-07-29

Abstract excerpt

1 The inference of biological relatedness from DNA sequence data has a wide array of applications, such as in the study of human disease, anthropology and ecology. One of the most common analytical frameworks for performing this inference is to genotype individuals for large numbers of independent genomewide markers and use population allele frequencies to infer the probability of identity-by-descent (IBD) given o...

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Literature Corpus work: 1b94ddea-4048-5983-b15f-58c79ffe62b8
DOI: 10.1101/023374

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