Article
Moment estimators of relatedness from low-depth whole-genome sequencing data.
BMC bioinformatics - 24 Jun 2022
Herzig Anthony F, Ciullo M, Leutenegger A-L, Perdry H
Abstract excerpt
BACKGROUND: Estimating relatedness is an important step for many genetic study designs. A variety of methods for estimating coefficients of pairwise relatedness from genotype data have been proposed. Both the kinship coefficient [Formula: see text] and the fraternity coefficient [Formula: see text] for all pairs of individuals are of interest. However, when dealing with low-depth sequencing or imputation data,...
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