Article

Size matters - the impact of nucleus size on results from spatial transcriptomics

2022-04-01

Abstract excerpt

Visium Spatial Gene Expression (ST) is a method combining histological spatial information with transcriptomics profiles directly from tissue sections. The use of spatial information has made it possible to discover novel modes of gene expression regulations. However, in the ST experiment, the nucleus size of cells may exceed the thickness of a tissue slice. This may, in turn, negatively affect comprehensive captu...

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Literature Corpus work: 1b6bb8c6-1071-5028-a635-65ae475d1010
DOI: 10.1101/2022.03.31.486657

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