Integrating gene expression and imaging data across Visium capture areas with visiumStitched

Abstract excerpt

<h4>Background</h4> Visium is a widely-used spatially-resolved transcriptomics assay available from 10x Genomics. Standard Visium capture areas (6.5mm by 6.5mm) limit the survey of larger tissue structures, but combining overlapping images and associated gene expression data allow for more complex study designs. Current software can handle nested or partial image overlaps, but is designed for merging up to two ca...

Topics

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• Cells
• Fluorescent Dyes
• Gene Expression Profiling
• Image Processing, Computer-Assisted
• Phenotype
• Single-cell and spatial transcriptomics
• Technology
• Transcriptome

Identifiers and source

Literature Corpus work

40cd9d95-2e33-5a71-a1c6-1d9ebcf68d72

DOI

10.1101/2024.08.08.607222