Article

Towards a Better Understanding of Batch Effects in Spatial Transcriptomics: Definition and Method Evaluation

2025-03-13

Abstract excerpt

<h4>Background</h4> Spatial transcriptomics (ST) enables high-resolution mapping of gene expression within tissue slices, providing detailed insights into tissue architecture and cellular interactions. However, batch effects, arising from non-biological variations in sample collection, processing, sequencing platforms, or experimental protocols, can obscure biological signals, hinder data integration, and impact...

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Literature Corpus work: 0dba6094-807c-5c34-b8e4-39da73217d7a
DOI: 10.1101/2025.03.12.642755

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