Article

The Effect of Resveratrol on Aortic Function in Patients with Marfan Syndrome – Rationale and Design of the Resvcue Marfan Trial.

2021-06-07

Abstract excerpt

<title>Abstract</title> <p><bold><italic>Background</italic></bold> Marfan syndrome (MFS) is a connective tissue disorder characterized by mutations in the fibrillin-1 (FBN1) gene. The most important manifestation is progressive enlargement of the aorta, ultimately leading to aortic dissection or rupture. Present day pharmacological treatment is based on drugs that decrease repetitive stress on the aorta and impr...

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Literature Corpus work: 1b5e89d7-1794-5dd2-8dcf-70a376ddad6b
DOI: 10.21203/rs.3.rs-434876/v1

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