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Article

Mechanical Force-Induced Specific MicroRNA Expression in Human Periodontal Ligament Stem Cells

1 Jan 2014

Abstract excerpt

It remains unclear how the expression of microRNAs (miRNAs) in human periodontal ligament stem cells (PDLSCs) might respond to mechanical stretch. To investigate specific miRNA expression in stretched PDLSCs, we used a Flexcell® FX-5000™ tension system to achieve external mechanical stimulation. Then, a custom-designed microarray assay was performed to investigate and describe the genome-wide differential...

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PMID: 25823370
DOI: 10.1159/000369613

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