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Multi-Target Mechanisms of Xiaobi Plaster in Lumbar Disc Degeneration: Insights from Network Pharmacology and Bioinformatics Analyses

2025-09-17

Abstract excerpt

<h4>Background</h4> Lumbar disc degeneration (LDD) is characterized by chronic inflammation, oxidative stress, and extracellular matrix (ECM) breakdown, yet current therapies provide only symptomatic relief. Xiaobi Plaster (XBG), a traditional Chinese transdermal herbal preparation, has shown clinical benefit, but its molecular mechanisms remain unclear. <h4>Methods</h4> We applied an integrative systems biology...

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Literature Corpus work
1a98df32-16b4-5dec-adb8-7e75bf76a9ca
DOI
10.1101/2025.09.11.675695
Open publication

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Multi-Target Mechanisms of Xiaobi Plaster in Lumbar Disc Degeneration: Insights from Network Pharmacology and Bioinformatics AnalysesDOI 10.1101/2025.09.11.675695
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