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Derivation and comprehensive analysis of ageing-related genes in intervertebral disc degeneration for prediction and immunology

24 Feb 2023

Abstract excerpt

Intervertebral disc degeneration (IDD) is triggered primarily by ageing, a process characterized by intrinsic, multifaceted and progressive characteristics. Regarding the crucial senescence genes and underlying regulatory mechanisms leading to the etiology of IDD, there is still some uncertainty. In this study, we used gene expression patterns from the GEO database to create a diagnostic model of IDD using...

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PMID: 36841375
DOI: 10.1016/j.mad.2023.111794

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