Back to search

Article

Network pharmacology and in silico approaches to uncover multitargeted mechanism of action of Zingiber zerumbet rhizomes for the treatment of idiopathic pulmonary fibrosis

2024-06-25

Abstract excerpt

Background Idiopathic pulmonary fibrosis (IPF) is a disease with high mortality, and there are only two specific drugs available for therapeutic management with limitations. The study aims to identify comprehensive therapeutic mechanisms of Zingiber zerumbet rhizomes (ZZR) to treat IPF by using network pharmacology followed battery of in silico studies. Methods The protein-protein interaction network was develope...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d8061c72-ae3e-5374-8f9e-a84a51bf3c03
DOI
10.12688/f1000research.142513.2
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Network pharmacology and in silico approaches to uncover multitargeted mechanism of action of Zingiber zerumbet rhizomes for the treatment of idiopathic pulmonary fibrosisDOI 10.12688/f1000research.142513.2
Exploring the role and mechanism of Astragalus membranaceus and radix paeoniae rubra in idiopathic pulmonary fibrosis through network pharmacology and experimental validationSemantic proximity
Therapeutic Role and Potential Mechanism of Astragalus Membranaceus (Huangqi) and Radix Paeoniae Rubra (Chishao) in Idiopathic Pulmonary Fibrosis – Network Pharmacology and Experimental ValidationSemantic proximity
Investigation of Anti-Epithelial-Mesenchymal Transition and Anti-Inflammation effects of Qing Fei Hua Xian Decotion on Pulmonary Fibrosis via Network Pharmacology and Experimental VerificationSemantic proximity
Exploring the Mechanism of Topical Application of Clematis Florida in the Treatment of Rheumatoid Arthritis through Network Pharmacology and Experimental ValidationSemantic proximity
A network pharmacology approach to determine the synergetic mechanisms of herb couple for treating rheumatic arthritisSemantic proximity
Unraveling the Therapeutic Mechanism of Saussurea involucrata against Rheumatoid Arthritis: A Network Pharmacology and Molecular Modeling-Based InvestigationSemantic proximity
Anti-inflammatory Properties of Fangji Huangqi Tang: Discovery Based on Network Pharmacology, Molecular Docking and Arrowsmith ToolsSemantic proximity
Drug Repurposing Through a Bioinformatics Pipeline Applied on Fibrotic DiseasesSemantic proximity
Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Angelicae Pubescentis Radix in the treatment of rheumatoid arthritisSemantic proximity
Integrative Analysis of the Therapeutic Mechanisms of Astragaloside IV in Idiopathic Pulmonary Fibrosis via Network Pharmacology and Molecular ValidationSemantic proximity
Integrated Bioinformatics, Network Pharmacology and Molecular Docking to Explore the Mechanisms of Taohong Siwu Decoction in the Treatment of TendinopathySemantic proximity
Cheminformatics and Pharmacological Network Analysis for the Prediction of Molecular Mechanism of Herbal Drug LigandsSemantic proximity
Select a neighboring publication to make it the new centre.