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Comprehensive analyses identify IRF8 in microglia as a possible regulatory target for Parkinson’s Disease

2023-10-10

Abstract excerpt

Parkinson's disease (PD) is a widespread degenerative disorder of the central nervous system. The gradual degeneration of dopaminergic neurons in the substantia nigra region is one of the primary pathological features of PD. Glial cells in SN are also linked to the pathological PD alterations. To discern the role of neurons and glial cells as well as their corresponding genetic modifications in PD, we utilized div...

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Literature Corpus work
1a9842f2-4f59-5e76-993f-78d23aab3958
DOI
10.21203/rs.3.rs-3412881/v1
Open publication

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Comprehensive analyses identify IRF8 in microglia as a possible regulatory target for Parkinson’s DiseaseDOI 10.21203/rs.3.rs-3412881/v1
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