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The Sle1 Cell Wall Amidase Controls Daughter Cell Splitting, Cell Size, and β-Lactam Resistance in Community Acquired Methicillin Resistant <i>Staphylococcus aureus</i> USA300

2019-09-19

Abstract excerpt

<h4>Summary</h4> Most clinically relevant methicillin resistant Staphylococcus aureus (MRSA) strains have become resistant to β-lactams antibiotics through horizontal acquisition of the mecA gene encoding PBP2a, a peptidoglycan transpeptidase with low affinity for β-lactams. The level of resistance conferred by mecA is, however, strain dependent and the mechanisms underlying this phenomenon remain poorly under...

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Literature Corpus work
1a87d33f-2d4a-559d-b138-651f996c8272
DOI
10.1101/772616
Open publication

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