Article

Investigating direct and indirect genetic effects in attention deficit hyperactivity disorder (ADHD) using parent-offspring trios

2022-04-16

Abstract excerpt

<h4>Background</h4> Attention deficit hyperactivity disorder (ADHD) is highly heritable, but little is known about the relative effects of transmitted (i.e. direct) and non-transmitted (i.e. indirect) common variant risks. Using parent-offspring trios, we tested whether polygenic liability for neurodevelopmental and psychiatric disorders and lower cognitive ability is over-transmitted to ADHD probands. We also tes...

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Literature Corpus work: 1a41ebed-2bfb-57f6-9eb7-ff4a78be6676
DOI: 10.1101/2022.04.11.22273180

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