CYPD limits HR+ mammary carcinogenesis in mice

Abstract excerpt

<title>Abstract</title> <p>Mitochondrial permeability transition (MPT)-driven necrosis and necroptosis are regulated variants of cell death that can drive inflammation or even promote antigen-specific immune responses. In oncological settings, indolent inflammatory reactions have been consistently associated with accelerated disease progression and resistance to treatment. Conversely, adaptive immune responses sp...

Topics

Open a Topic to create a Post that cites this publication.

• Autophagy in Disease and Therapy
• Cancer-related Molecular Pathways
• Cell death mechanisms and regulation
• Inflammatory mediators and NSAID effects
• Mitochondrial Function and Pathology
• NF-κB Signaling Pathways
• Nuclear Structure and Function
• Ubiquitin and proteasome pathways

Identifiers and source

Literature Corpus work

1a1c83c1-8896-56fe-88a3-a073d50d0922

DOI

10.21203/rs.3.rs-6265353/v1