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Personalized Neoantigen Vaccines Synergize with Immune Checkpoint Therapy and CD8-Targeted Cytokines to Control B-Cell Lymphoma

2026-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Personalized neoantigen (neoAg) vaccines have shown clinical promise in solid tumors 1–8 , yet their efficacy and mechanism of action in hematopoietic malignancies remain poorly defined 9–11 . Herein, we establish an immunocompetent syngeneic A20 B-cell lymphoma platform to test the efficacy of neoAg vaccines used either as mono- or combinatorial therapies with other immunotherapies 12–17 . W...

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Literature Corpus work
19bff573-f862-56c9-97ad-3a2d98b40124
DOI
10.64898/2026.08.02.742304
Open publication

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Personalized Neoantigen Vaccines Synergize with Immune Checkpoint Therapy and CD8-Targeted Cytokines to Control B-Cell LymphomaDOI 10.64898/2026.08.02.742304
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