Article

Whole exome sequencing in patients with ossification of the spinal ligaments

2022-04-07

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> The clinical presentations of ossification of spinal ligament (OSL) are majorly myelopathy and/or radiculopathy, with serious neurological pathology resulting in paralysis of extremities and disturbances of motility (motor function) lowering the quality of life. Currently, studies find that missense single nucleotide polymorphisms (SNPs) play a vital role in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 19b82631-9550-533d-9f35-629e0acfb5c4
DOI: 10.21203/rs.3.rs-406569/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole exome sequencing in patients with ossification of the spinal ligamentsDOI 10.21203/rs.3.rs-406569/v2Read

[Genomic analysis of ossification of the posterior longitudinal ligament].Semantic proximity Read

Unveiling the genetic variation of severe continuous/mixed-type ossification of the posterior longitudinal ligament by whole-exome sequencing and bioinformatic analysis.Semantic proximity Read

A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine.Semantic proximity Read

Whole-exome sequencing: discovering genetic causes of orthopaedic disorders.Semantic proximity Read

The identification of novel gene mutations for degenerative lumbar spinal stenosis using whole-exome sequencing in a Chinese cohort.Semantic proximity Read

Targeted next-generation sequencing reveals multiple deleterious variants in OPLL-associated genes.Semantic proximity Read

Identification of Novel Gene Mutations in Degenerative Lumbar Spinal Stenosis Using Whole Exome Sequencing in Chinese PopulationSemantic proximity Read

Comprehensive Analysis of Aberrantly Expressed CircRNAs in the Ossification of the Posterior Longitudinal LigamentSemantic proximity Read

Genetic insights into ossification of the posterior longitudinal ligament of the spineSemantic proximity Read

Exome Sequencing Reveals Novel Variants in Genetic Skeletal Disorders: Insights From a Cohort in Southwest Iran.Semantic proximity Read

Association Study of Fibroblast Growth Factor 2 and Fibroblast Growth Factor Receptors Gene Polymorphism in Korean Ossification of the Posterior Longitudinal Ligament PatientsSemantic proximity Read

The Pathogenesis of Ossification of the Posterior Longitudinal LigamentSemantic proximity Read