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CD38 expression by antigen-specific CD4 T cells correlates with sputum bacterial load at time of tuberculosis diagnosis and is significantly restored 5-months after treatment initiation

2022-01-28

Abstract excerpt

<h4>ABSTRACT</h4> T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising candidates to attest the presence of an active infection by Mycobacterium tuberculosis ( Mtb ). Reciprocally, their modulation may be used to assess antibiotic treatment efficacy and eventually attest disease resolution. We hypothesized that the phenotype of Mtb -specific T cells may be quantitatively impac...

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Literature Corpus work
19845821-000e-5218-8a95-06c7fa8bade6
DOI
10.1101/2022.01.26.22269875
Open publication

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CD38 expression by antigen-specific CD4 T cells correlates with sputum bacterial load at time of tuberculosis diagnosis and is significantly restored 5-months after treatment initiationDOI 10.1101/2022.01.26.22269875
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