Article

The inhibitory effect of isavuconazole on almonertinib metabolism and its underlying mechanism

2024-03-25

Abstract excerpt

<title>Abstract</title> <p>As a third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), almonertinib is effective for the treatment of non-small cell lung cancer (NSCLC), and there is not much interaction research on its combination with other drugs. Here, an ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was validated and enabled stable and rapid det...

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Literature Corpus work: 195cc47b-aed2-55c5-8698-43fa6e090c72
DOI: 10.21203/rs.3.rs-4116071/v1

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