Article

Aberrant DNA Damage Response and DNA Repair Pathway in High Glucose Conditions

2018-06-23

Abstract excerpt

Background: Higher cancer rates and more aggressive behavior of certain cancers have been reported in populations with diabetes mellitus. This association has been attributed in part to the excessive reactive oxygen species generated in diabetic conditions and to the resulting oxidative DNA damage. It is not known, however, whether oxidative stress is the only contributing factor to genomic instability in patients...

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Literature Corpus work: 195a4aa7-644e-5557-9225-845b7eb5b1db
DOI: 10.6000/1929-2279.2018.07.03.1

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