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Hyperglycemia Differentially Affects Maternal and Fetal DNA Integrity and DNA Damage Response

1 Jan 2016

Abstract excerpt

OBJECTIVE: Investigate the DNA damage and its cellular response in blood samples from both mother and the umbilical cord of pregnancies complicated by hyperglycemia. METHODS: A total of 144 subjects were divided into 4 groups: normoglycemia (ND; 46 cases), mild gestational hyperglycemia (MGH; 30 cases), gestational diabetes mellitus (GDM; 45 cases) and type-2 diabetes mellitus (DM2; 23 cases). Peripheral blood...

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PMID: 27019630
DOI: 10.7150/ijbs.12815

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