Article

Pentagalloylglucose ameliorates acute respiratory distress syndrome by targeting PFKFB2-mediated neutrophil glycolysis and inflammation

2026-08-11

Abstract excerpt

<title>Abstract</title> <p>Background Acute respiratory distress syndrome (ARDS) is a life-threatening clinical syndrome characterized by acute hypoxemic respiratory failure, with mortality rates ranging from 30% to 50% in critically ill patients. Despite decades of research, effective targeted therapies remain limited. Metabolic reprogramming and excessive neutrophil-mediated inflammation are central pathologic...

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Literature Corpus work: 193225ff-ff1f-5fa5-a8dc-0c213cbe1673
DOI: 10.21203/rs.3.rs-10380478/v1

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