Article

Interactome comparison of human embryonic stem cell lines with the inner cell mass and trophectoderm

2018-09-07

Abstract excerpt

Human embryonic stem cells (hESCs) derived from the pluripotent Inner cell mass (ICM) of the blastocyst are fundamental tools for understanding human development, yet are not identical to their tissue of origin. To investigate this divergence we compared the transcriptomes of genetically paired ICM and trophectoderm (TE) samples with three hESC lines: MAN1, HUES3 and HUES7 at similar passage. We generated inferred...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1930ef06-a526-5ffe-ac2b-692fd8a28a2d
DOI: 10.1101/411439

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Interactome comparison of human embryonic stem cell lines with the inner cell mass and trophectodermDOI 10.1101/411439Read

Network based meta-analysis prediction of microenvironmental relays involved in stemness of human embryonic stem cellsSemantic proximity Read

Gene expression profiles of human inner cell mass cells and embryonic stem cellsSemantic proximity Read

Primary Differentiation in the Human Blastocyst: Comparative Molecular Portraits of Inner Cell Mass and Trophectoderm CellsSemantic proximity Read

Deciphering transcriptional regulation in human embryonic stem cells specified towards a trophoblast fateSemantic proximity Read

Combined mRNA and microRNA profiling reveals that miR-148a and miR-20b control human mesenchymal stem cell phenotype via EPAS1.Semantic proximity Read

Constitutional activation of BMP4 and WNT signalling in hESC results in impaired mesendoderm differentiationSemantic proximity Read

Possible linkages between the inner and outer cellular states of human induced pluripotent stem cellsSemantic proximity Read

Defining stemness of human embryonic stem cells : a systems biology approachSemantic proximity Read

Monosomy X in isogenic human iPSC-derived trophoblast model impacts expression modules preserved in human placentaSemantic proximity Read

BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryoSemantic proximity Read

BMP-treated human embryonic stem cells transcriptionally resemble amnion cells in the monkey embryoSemantic proximity Read

Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors.Semantic proximity Read