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Deciphering transcriptional regulation in human embryonic stem cells specified towards a trophoblast fate

4 Dec 2017

Abstract excerpt

Differentiated human embryonic stem cells (hESC) continue to provide a model for studying early trophoblast cells (TB), but many questions have been raised regarding their true identity. Therefore, we carried out a global and unbiased analysis on previously published transcriptomic profiles for hESC differentiated to TB by means of bone morphogenetic protein-4 and inhibitors of activin A and fibroblast growth...

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PMID: 29222466
DOI: 10.1038/s41598-017-17614-5

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